Silver nanoparticles inhibit the function of hypoxia-inducible factor-1 and target genes: insight into the cytotoxicity and antiangiogenesis

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that is activated upon exposure to hypoxic stress. It modulates a number of cellular responses including proliferation, apoptosis, angiogenesis, and metabolism by activating a panel of target genes in response to hypoxia. The HIF-1 level i...

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Detalles Bibliográficos
Autores principales: Yang, Tieshan, Yao, Qian, Cao, Fei, Liu, Qianqian, Liu, Binlei, Wang, Xiu-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154724/
https://www.ncbi.nlm.nih.gov/pubmed/27994464
http://dx.doi.org/10.2147/IJN.S109695

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