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Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes

Because antigen-stimulated naive T cells either die as effectors or enter the activated/memory pool, continuous egress of new T lymphocytes from thymus is essential for maintenance of peripheral immune homeostasis. Unexpectedly, we found that systemic infection with the protozoan Toxoplasma gondii t...

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Detalles Bibliográficos
Autores principales:	Kugler, David G., Flomerfelt, Francis A., Costa, Diego L., Laky, Karen, Kamenyeva, Olena, Mittelstadt, Paul R., Gress, Ronald E., Rosshart, Stephan P., Rehermann, Barbara, Ashwell, Jonathan D., Sher, Alan, Jankovic, Dragana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154934/ https://www.ncbi.nlm.nih.gov/pubmed/27849554 http://dx.doi.org/10.1084/jem.20151636

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