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Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion

The host responds to virus infection by activating type I interferon (IFN) signaling leading to expression of IFN-stimulated genes (ISGs). Dysregulation of the IFN response results in inflammatory diseases and chronic infections. In this study, we demonstrate that IFN regulatory factor 2 (IRF2), an...

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Detalles Bibliográficos
Autores principales:	Li, Melody M.H., Bozzacco, Leonia, Hoffmann, Hans-Heinrich, Breton, Gaëlle, Loschko, Jakob, Xiao, Jing W., Monette, Sébastien, Rice, Charles M., MacDonald, Margaret R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2016
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154937/ https://www.ncbi.nlm.nih.gov/pubmed/27899441 http://dx.doi.org/10.1084/jem.20160303

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