Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance

Mixed fungal infection and acquired echinocandin resistance of Candida spp. remain infrequent. In this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three common Candida species (C. albicans, C. glabrata, C. tropicalis). Further...

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Autores principales: Grosset, Marine, Desnos-Ollivier, Marie, Godet, Cendrine, Kauffmann-Lacroix, Catherine, Cazenave-Roblot, France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155041/
https://www.ncbi.nlm.nih.gov/pubmed/27995055
http://dx.doi.org/10.1016/j.mmcr.2016.12.004
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author Grosset, Marine
Desnos-Ollivier, Marie
Godet, Cendrine
Kauffmann-Lacroix, Catherine
Cazenave-Roblot, France
author_facet Grosset, Marine
Desnos-Ollivier, Marie
Godet, Cendrine
Kauffmann-Lacroix, Catherine
Cazenave-Roblot, France
author_sort Grosset, Marine
collection PubMed
description Mixed fungal infection and acquired echinocandin resistance of Candida spp. remain infrequent. In this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three common Candida species (C. albicans, C. glabrata, C. tropicalis). Furthermore, consecutive isolates from blood cultures and heart valve were found resistant to azoles (C. tropicalis) and to echinocandin with either novel (C. tropicalis) or previously described (C. albicans) missense mutations in the Fks gene.
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spelling pubmed-51550412016-12-19 Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance Grosset, Marine Desnos-Ollivier, Marie Godet, Cendrine Kauffmann-Lacroix, Catherine Cazenave-Roblot, France Med Mycol Case Rep Case Report Mixed fungal infection and acquired echinocandin resistance of Candida spp. remain infrequent. In this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three common Candida species (C. albicans, C. glabrata, C. tropicalis). Furthermore, consecutive isolates from blood cultures and heart valve were found resistant to azoles (C. tropicalis) and to echinocandin with either novel (C. tropicalis) or previously described (C. albicans) missense mutations in the Fks gene. Elsevier 2016-12-07 /pmc/articles/PMC5155041/ /pubmed/27995055 http://dx.doi.org/10.1016/j.mmcr.2016.12.004 Text en © 2016 Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Grosset, Marine
Desnos-Ollivier, Marie
Godet, Cendrine
Kauffmann-Lacroix, Catherine
Cazenave-Roblot, France
Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
title Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
title_full Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
title_fullStr Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
title_full_unstemmed Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
title_short Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance
title_sort recurrent episodes of candidemia due to candida glabrata, candida tropicalis and candida albicans with acquired echinocandin resistance
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155041/
https://www.ncbi.nlm.nih.gov/pubmed/27995055
http://dx.doi.org/10.1016/j.mmcr.2016.12.004
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