Doxycycline Inhibits IL-17-Stimulated MMP-9 Expression by Downregulating ERK1/2 Activation: Implications in Myogenic Differentiation

Interleukin 17 (IL-17) is a cytokine with pleiotropic effects associated with several inflammatory diseases. Although elevated levels of IL-17 have been described in inflammatory myopathies, its role in muscle remodeling and regeneration is still unknown. Excessive extracellular matrix degradation i...

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Detalles Bibliográficos
Autores principales: Obradović, Hristina, Krstić, Jelena, Kukolj, Tamara, Trivanović, Drenka, Đorđević, Ivana Okić, Mojsilović, Slavko, Jauković, Aleksandra, Jovčić, Gordana, Bugarski, Diana, Santibañez, Juan Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155103/
https://www.ncbi.nlm.nih.gov/pubmed/28042204
http://dx.doi.org/10.1155/2016/2939658

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