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Adiponectin Protects against Glutamate-Induced Excitotoxicity via Activating SIRT1-Dependent PGC-1α Expression in HT22 Hippocampal Neurons

Glutamate- (Glu-) induced excitotoxicity plays a critical role in stroke. This study aimed to investigate the effects of APN on Glu-induced injury in HT22 neurons. HT22 neurons were treated with Glu in the absence or the presence of an APN peptide. Cell viability was assessed using the MTT assay, wh...

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Detalles Bibliográficos
Autores principales:	Yue, Liang, Zhao, Lei, Liu, Haixiao, Li, Xia, Wang, Bodong, Guo, Hao, Gao, Li, Feng, Dayun, Qu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155107/ https://www.ncbi.nlm.nih.gov/pubmed/28042384 http://dx.doi.org/10.1155/2016/2957354

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