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Antigen-Specific IFN-γ Responses Correlate with the Activity of M. tuberculosis Infection but Are Not Associated with the Severity of Tuberculosis Disease

IFN-γ is a key cytokine in antituberculosis (TB) defense. However, how the levels of its secretion affect M. tuberculosis (Mtb) infection is not clear. We have analyzed associations between IFN-γ responses measured in QuantiFERON®-TB Gold In-tube (QFT) assay, TB disease severity, and Mtb infection a...

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Detalles Bibliográficos
Autores principales:	Nikitina, Irina Yu., Panteleev, Alexander V., Sosunova, Ekaterina V., Karpina, Natalya L., Bagdasarian, Tatef R., Burmistrova, Irina A., Andreevskaya, Sofia N., Chernousova, Larisa N., Vasilyeva, Irina A., Lyadova, Irina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155109/ https://www.ncbi.nlm.nih.gov/pubmed/28042583 http://dx.doi.org/10.1155/2016/7249369

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