Cargando…

The 5′UTR variant of ERCC5 fails to influence outcomes in ovarian and lung cancer patients undergoing treatment with platinum-based drugs

The common polymorphic variant in the 5′ untranslated region of the excision repair cross-complementation group 5 (ERCC5) gene was described to generate an upstream open reading frame that regulates both the basal ERCC5 expression and its ability to be synthesized following DNA damage. This variant...

Descripción completa

Detalles Bibliográficos
Autores principales: Rulli, Eliana, Guffanti, Federica, Caiola, Elisa, Ganzinelli, Monica, Damia, Giovanna, Garassino, Marina C., Piva, Sheila, Ceppi, Lorenzo, Broggini, Massimo, Marabese, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155271/
https://www.ncbi.nlm.nih.gov/pubmed/27966655
http://dx.doi.org/10.1038/srep39217

Ejemplares similares