Cargando…
Sympathetic neurons are a powerful driver of myocyte function in cardiovascular disease
Many therapeutic interventions in disease states of heightened cardiac sympathetic activity are targeted to the myocytes. However, emerging clinical data highlights a dominant role in disease progression by the neurons themselves. Here we describe a novel experimental model of the peripheral neuro-c...
Autores principales: | Larsen, Hege E., Lefkimmiatis, Konstantinos, Paterson, David J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155272/ https://www.ncbi.nlm.nih.gov/pubmed/27966588 http://dx.doi.org/10.1038/srep38898 |
Ejemplares similares
-
Human induced pluripotent stem cell-derived cardiac myocytes and sympathetic neurons in disease modelling
por: Li, Ni, et al.
Publicado: (2023) -
Abnormal Cyclic Nucleotide Signaling at the Outer Mitochondrial Membrane In Sympathetic Neurons During the Early Stages of Hypertension
por: Li, Dan, et al.
Publicado: (2022) -
Healthy cardiac myocytes can decrease sympathetic hyperexcitability in the early stages of hypertension
por: Davis, Harvey, et al.
Publicado: (2022) -
Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes
por: Richards, Mark, et al.
Publicado: (2016) -
Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics
por: Burton, Rebecca-Ann B., et al.
Publicado: (2020)