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Subtype-specific structural constraints in the evolution of influenza A virus hemagglutinin genes
The influenza A virus genome consists of eight RNA segments. RNA structures within these segments and complementary (cRNA) and protein-coding mRNAs may play a role in virus replication. Here, conserved putative secondary structures that impose significant evolutionary constraints on the gene segment...
Autores principales: | Gultyaev, Alexander P., Spronken, Monique I., Richard, Mathilde, Schrauwen, Eefje J. A., Olsthoorn, René C. L., Fouchier, Ron A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155281/ https://www.ncbi.nlm.nih.gov/pubmed/27966593 http://dx.doi.org/10.1038/srep38892 |
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