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Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review
BACKGROUND: Colonic mural thickening is often a finding in standard computed tomography (CT) scans of the abdomen. It often presents clinician with a dilemma on when a further endoscopic evaluation is needed, especially in the absence of guidelines. The aim of this systematic review is to evaluate t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155394/ https://www.ncbi.nlm.nih.gov/pubmed/27964739 http://dx.doi.org/10.1186/s13643-016-0381-7 |
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author | Chandrapalan, Subashini Tahir, Faraz Sinha, Rakesh Arasaradnam, Ramesh |
author_facet | Chandrapalan, Subashini Tahir, Faraz Sinha, Rakesh Arasaradnam, Ramesh |
author_sort | Chandrapalan, Subashini |
collection | PubMed |
description | BACKGROUND: Colonic mural thickening is often a finding in standard computed tomography (CT) scans of the abdomen. It often presents clinician with a dilemma on when a further endoscopic evaluation is needed, especially in the absence of guidelines. The aim of this systematic review is to evaluate the significance of bowel wall thickening and to assess its correlation with endoscopy. METHODS: This systematic review will be reported in accordance with the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. The search strategy will initially be developed in MEDLINE and adapted for use in EMBASE, MEDLINE, NHS evidence and TRIP. Two reviewers will independently conduct a study selection, data extraction and risk of bias assessment for the screened studies. Data synthesis will be conducted using Review Manager software 5.3. The outcome of any dichotomous data will be presented as relative risk with confidence intervals. DISCUSSION: It is extremely useful for the practising clinician to know which patients need further endoscopic evaluation. Even though there are several studies on this issue, none of them have attempted to produce a systematic review. We hope this systematic review will provide a substantiate evidence for future clinical practice. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016039378 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13643-016-0381-7) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5155394 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-51553942016-12-20 Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review Chandrapalan, Subashini Tahir, Faraz Sinha, Rakesh Arasaradnam, Ramesh Syst Rev Protocol BACKGROUND: Colonic mural thickening is often a finding in standard computed tomography (CT) scans of the abdomen. It often presents clinician with a dilemma on when a further endoscopic evaluation is needed, especially in the absence of guidelines. The aim of this systematic review is to evaluate the significance of bowel wall thickening and to assess its correlation with endoscopy. METHODS: This systematic review will be reported in accordance with the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. The search strategy will initially be developed in MEDLINE and adapted for use in EMBASE, MEDLINE, NHS evidence and TRIP. Two reviewers will independently conduct a study selection, data extraction and risk of bias assessment for the screened studies. Data synthesis will be conducted using Review Manager software 5.3. The outcome of any dichotomous data will be presented as relative risk with confidence intervals. DISCUSSION: It is extremely useful for the practising clinician to know which patients need further endoscopic evaluation. Even though there are several studies on this issue, none of them have attempted to produce a systematic review. We hope this systematic review will provide a substantiate evidence for future clinical practice. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016039378 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13643-016-0381-7) contains supplementary material, which is available to authorized users. BioMed Central 2016-12-13 /pmc/articles/PMC5155394/ /pubmed/27964739 http://dx.doi.org/10.1186/s13643-016-0381-7 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Protocol Chandrapalan, Subashini Tahir, Faraz Sinha, Rakesh Arasaradnam, Ramesh Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review |
title | Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review |
title_full | Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review |
title_fullStr | Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review |
title_full_unstemmed | Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review |
title_short | Colonic thickening on computed tomography—does it correlate with endoscopic findings? A protocol for systematic review |
title_sort | colonic thickening on computed tomography—does it correlate with endoscopic findings? a protocol for systematic review |
topic | Protocol |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155394/ https://www.ncbi.nlm.nih.gov/pubmed/27964739 http://dx.doi.org/10.1186/s13643-016-0381-7 |
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