Eyelid and feet edema induced by pemetrexed

Pemetrexed is an anti-metabolite that targets multiple enzymes in folate pathway. The main toxicities associated with pemetrexed are asthenia, nausea, diarrhea, myelosuppression, and rash. Few cases of pemetrexed induced cutaneous adverse event have been reported, mainly periorbital-facial edema and...

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Detalles Bibliográficos
Autores principales: Kastalli, Sarrah, Charfi, Ons, Sahnoun, Rym, Lakhoua, Ghozlane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Drug Watch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155483/
https://www.ncbi.nlm.nih.gov/pubmed/28066120
http://dx.doi.org/10.4103/0253-7613.194862
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author Kastalli, Sarrah
Charfi, Ons
Sahnoun, Rym
Lakhoua, Ghozlane
author_facet Kastalli, Sarrah
Charfi, Ons
Sahnoun, Rym
Lakhoua, Ghozlane
author_sort Kastalli, Sarrah
collection PubMed
description Pemetrexed is an anti-metabolite that targets multiple enzymes in folate pathway. The main toxicities associated with pemetrexed are asthenia, nausea, diarrhea, myelosuppression, and rash. Few cases of pemetrexed induced cutaneous adverse event have been reported, mainly periorbital-facial edema and edema of the limbs. We report a case of pemetrexed-induced edema of the eyelid and feet in a patient with adenocarcinoma of the lung.
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spelling pubmed-51554832017-01-06 Eyelid and feet edema induced by pemetrexed Kastalli, Sarrah Charfi, Ons Sahnoun, Rym Lakhoua, Ghozlane Indian J Pharmacol Drug Watch Pemetrexed is an anti-metabolite that targets multiple enzymes in folate pathway. The main toxicities associated with pemetrexed are asthenia, nausea, diarrhea, myelosuppression, and rash. Few cases of pemetrexed induced cutaneous adverse event have been reported, mainly periorbital-facial edema and edema of the limbs. We report a case of pemetrexed-induced edema of the eyelid and feet in a patient with adenocarcinoma of the lung. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5155483/ /pubmed/28066120 http://dx.doi.org/10.4103/0253-7613.194862 Text en Copyright: © Indian Journal of Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Drug Watch
Kastalli, Sarrah
Charfi, Ons
Sahnoun, Rym
Lakhoua, Ghozlane
Eyelid and feet edema induced by pemetrexed
title Eyelid and feet edema induced by pemetrexed
title_full Eyelid and feet edema induced by pemetrexed
title_fullStr Eyelid and feet edema induced by pemetrexed
title_full_unstemmed Eyelid and feet edema induced by pemetrexed
title_short Eyelid and feet edema induced by pemetrexed
title_sort eyelid and feet edema induced by pemetrexed
topic Drug Watch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155483/
https://www.ncbi.nlm.nih.gov/pubmed/28066120
http://dx.doi.org/10.4103/0253-7613.194862
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AT sahnounrym eyelidandfeetedemainducedbypemetrexed
AT lakhouaghozlane eyelidandfeetedemainducedbypemetrexed

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