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Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression
FOXF1 heterozygous point mutations and genomic deletions have been reported in newborns with the neonatally lethal lung developmental disorder, alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV). However, no gain-of-function mutations in FOXF1 have been identified yet in any...
Autores principales: | Dharmadhikari, Avinash V., Sun, Jenny J., Gogolewski, Krzysztof, Carofino, Brandi L., Ustiyan, Vladimir, Hill, Misty, Majewski, Tadeusz, Szafranski, Przemyslaw, Justice, Monica J., Ray, Russell S., Dickinson, Mary E., Kalinichenko, Vladimir V., Gambin, Anna, Stankiewicz, Paweł |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155529/ https://www.ncbi.nlm.nih.gov/pubmed/27638768 http://dx.doi.org/10.1242/bio.019208 |
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