Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development

The ADAMTS family comprises 19 secreted metalloproteinases that cleave extracellular matrix components and have diverse functions in numerous disease and physiological contexts. A number of them remain ‘orphan’ proteases and among them is ADAMTS18, which has been implicated in developmental eye diso...

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Detalles Bibliográficos
Autores principales: Ataca, Dalya, Caikovski, Marian, Piersigilli, Alessandra, Moulin, Alexandre, Benarafa, Charaf, Earp, Sarah E., Guri, Yakir, Kostic, Corinne, Arsenivic, Yvan, Soininen, Raija, Apte, Suneel S., Brisken, Cathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155532/
https://www.ncbi.nlm.nih.gov/pubmed/27638769
http://dx.doi.org/10.1242/bio.019711

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