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Whole cell vaccination using immunogenic cell death by an oncolytic adenovirus is effective against a colorectal cancer model
Cancer vaccine application is limited to specific cancer types because few cancer-associated antigens are known to induce tumor rejection. Accordingly, we assessed the utility of Ad881, an oncolytic adenovirus in which viral replication was strictly regulated by the cancer-specific midkine promoter,...
Autores principales: | Yamano, Tomoki, Kubo, Shuji, Fukumoto, Miki, Yano, Aya, Mawatari-Furukawa, Yuki, Okamura, Haruki, Tomita, Naohiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155634/ https://www.ncbi.nlm.nih.gov/pubmed/28035331 http://dx.doi.org/10.1038/mto.2016.31 |
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