Interim estimates of the effectiveness of influenza vaccination against influenza‐associated hospitalization in children in Hong Kong, 2015–16

From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6 months to 17 years of age admitted to hospital with a febrile acute respiratory infection in our test‐negative study. Information on receipt of 2015–16 northern hemisphere inactivated influenza vaccination was elicited from p...

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Detalles Bibliográficos
Autores principales: Cowling, Benjamin J., Kwan, Mike Y. W., Wong, Joshua S. C., Feng, Shuo, Leung, Chi‐Wai, Chan, Eunice L. Y., Chan, Kwok‐Hung, Ng, Tak‐Keung, To, Wing‐Kin, Peiris, Malik J. S., Chiu, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155726/
https://www.ncbi.nlm.nih.gov/pubmed/27313064
http://dx.doi.org/10.1111/irv.12399
Descripción
Sumario:From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6 months to 17 years of age admitted to hospital with a febrile acute respiratory infection in our test‐negative study. Information on receipt of 2015–16 northern hemisphere inactivated influenza vaccination was elicited from parents or legal guardians. Using conditional logistic regression adjusting for age and matching on calendar time, we estimated influenza vaccine effectiveness against hospitalization with influenza A or B to be 79.2% (95% confidence interval: 42.0%–92.4%). Annual influenza vaccination should be more widely used in children in Hong Kong.

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