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Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5

Leukocidin ED (LukED) is a bicomponent pore-forming toxin produced by Staphylococcus aureus that lyses host cells by targeting the chemokine receptors CC chemokine receptor type 5 (CCR5), CXCR1, CXCR2, and DARC. In addition to its role as a receptor for LukED, CCR5 is the major coreceptor for primar...

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Detalles Bibliográficos
Autores principales:	Tam, Kayan, Schultz, Megan, Reyes-Robles, Tamara, Vanwalscappel, Bénédicte, Horton, Joshua, Alonzo, Francis, Wu, Beili, Landau, Nathaniel R., Torres, Victor J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156306/ https://www.ncbi.nlm.nih.gov/pubmed/27965453 http://dx.doi.org/10.1128/mBio.02024-16

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