Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia

Tumor relapse is associated with dismal prognosis, but responsible biological principles remain incompletely understood. To isolate and characterize relapse-inducing cells, we used genetic engineering and proliferation-sensitive dyes in patient-derived xenografts of acute lymphoblastic leukemia (ALL...

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Detalles Bibliográficos
Autores principales: Ebinger, Sarah, Özdemir, Erbey Ziya, Ziegenhain, Christoph, Tiedt, Sebastian, Castro Alves, Catarina, Grunert, Michaela, Dworzak, Michael, Lutz, Christoph, Turati, Virginia A., Enver, Tariq, Horny, Hans-Peter, Sotlar, Karl, Parekh, Swati, Spiekermann, Karsten, Hiddemann, Wolfgang, Schepers, Aloys, Polzer, Bernhard, Kirsch, Stefan, Hoffmann, Martin, Knapp, Bettina, Hasenauer, Jan, Pfeifer, Heike, Panzer-Grümayer, Renate, Enard, Wolfgang, Gires, Olivier, Jeremias, Irmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156313/
https://www.ncbi.nlm.nih.gov/pubmed/27916615
http://dx.doi.org/10.1016/j.ccell.2016.11.002

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