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The contribution of pUL74 to growth of human cytomegalovirus is masked in the presence of RL13 and UL128 expression
The glycoproteins gH and gL of human cytomegalovirus (HCMV) form a complex either with pUL74 (trimeric complex) or with proteins of the UL128 locus (pentameric complex). While the pentameric complex is dispensable for viral growth in fibroblasts, deletion of pUL74 causes a small plaque phenotype in...
Autores principales: | Laib Sampaio, Kerstin, Stegmann, Cora, Brizic, Ilija, Adler, Barbara, Stanton, Richard J., Sinzger, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156331/ https://www.ncbi.nlm.nih.gov/pubmed/27050420 http://dx.doi.org/10.1099/jgv.0.000475 |
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