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Effects of Low Dose Metformin on Metabolic Traits in Clozapine-Treated Schizophrenia Patients: An Exploratory Twelve-Week Randomized, Double-Blind, Placebo-Controlled Study

BACKGROUND: Metformin has been used for alleviating metabolic abnormalities in patients with schizophrenia. The lowest dose of metformin to treat metabolic abnormalities in clozapine-treated patients is 1000 mg/d. This study was designed to determine whether metformin at 500 mg/d and 1000 mg/d is ef...

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Detalles Bibliográficos
Autores principales: Chiu, Chih-Chiang, Lu, Mong-Liang, Huang, Ming-Chyi, Chen, Po-Yu, Lin, Yen-Kuang, Lin, Shih-Ku, Chen, Chun-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156367/
https://www.ncbi.nlm.nih.gov/pubmed/27973619
http://dx.doi.org/10.1371/journal.pone.0168347

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