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Effects of Low Dose Metformin on Metabolic Traits in Clozapine-Treated Schizophrenia Patients: An Exploratory Twelve-Week Randomized, Double-Blind, Placebo-Controlled Study
BACKGROUND: Metformin has been used for alleviating metabolic abnormalities in patients with schizophrenia. The lowest dose of metformin to treat metabolic abnormalities in clozapine-treated patients is 1000 mg/d. This study was designed to determine whether metformin at 500 mg/d and 1000 mg/d is ef...
Autores principales: | Chiu, Chih-Chiang, Lu, Mong-Liang, Huang, Ming-Chyi, Chen, Po-Yu, Lin, Yen-Kuang, Lin, Shih-Ku, Chen, Chun-Hsin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156367/ https://www.ncbi.nlm.nih.gov/pubmed/27973619 http://dx.doi.org/10.1371/journal.pone.0168347 |
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