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Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide
This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-pi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156471/ https://www.ncbi.nlm.nih.gov/pubmed/27995169 http://dx.doi.org/10.1016/j.dib.2016.07.019 |
| _version_ | 1782481271393353728 |
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| author | Déciga-Campos, Myrna Navarrete-Vázquez, Gabriel López-Muñoz, Francisco Javier Librowski, Tadeusz Sánchez-Recillas, Amanda Yañez-Pérez, Victor Ortiz-Andrade, Rolffy |
| author_facet | Déciga-Campos, Myrna Navarrete-Vázquez, Gabriel López-Muñoz, Francisco Javier Librowski, Tadeusz Sánchez-Recillas, Amanda Yañez-Pérez, Victor Ortiz-Andrade, Rolffy |
| author_sort | Déciga-Campos, Myrna |
| collection | PubMed |
| description | This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine” Déciga-Campos M., Navarrete-Vázquez G., López-Muñoz F.J., Librowski T., Sánchez-Recillas A., Yañez-Pérez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L.) and mice. Also, we used the micronucleus assay to determine genotoxicity. We used the platform admetSAR to predict absorption properties of LIA and lidocaine. |
| format | Online Article Text |
| id | pubmed-5156471 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-51564712016-12-19 Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide Déciga-Campos, Myrna Navarrete-Vázquez, Gabriel López-Muñoz, Francisco Javier Librowski, Tadeusz Sánchez-Recillas, Amanda Yañez-Pérez, Victor Ortiz-Andrade, Rolffy Data Brief Data Article This text presents complementary data corresponding to pharmacological and toxicological characterization of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide (LIA) compound. These data support our research article entitled “Pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)acetamide, a novel analog of lidocaine” Déciga-Campos M., Navarrete-Vázquez G., López-Muñoz F.J., Librowski T., Sánchez-Recillas A., Yañez-Pérez V., Ortiz-Andrade R. (2016) [1]. Toxicity was predicted through the ACD/ToxSuite software and evaluated in vivo using brine shrimp larvae (Artemia salina L.) and mice. Also, we used the micronucleus assay to determine genotoxicity. We used the platform admetSAR to predict absorption properties of LIA and lidocaine. Elsevier 2016-07-16 /pmc/articles/PMC5156471/ /pubmed/27995169 http://dx.doi.org/10.1016/j.dib.2016.07.019 Text en © 2016 The Authors. Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Data Article Déciga-Campos, Myrna Navarrete-Vázquez, Gabriel López-Muñoz, Francisco Javier Librowski, Tadeusz Sánchez-Recillas, Amanda Yañez-Pérez, Victor Ortiz-Andrade, Rolffy Complementary pharmacological and toxicological characterization data on the pharmacological profile of N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl) acetamide |
| title | Complementary pharmacological and toxicological characterization data
on the pharmacological profile of
N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)
acetamide |
| title_full | Complementary pharmacological and toxicological characterization data
on the pharmacological profile of
N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)
acetamide |
| title_fullStr | Complementary pharmacological and toxicological characterization data
on the pharmacological profile of
N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)
acetamide |
| title_full_unstemmed | Complementary pharmacological and toxicological characterization data
on the pharmacological profile of
N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)
acetamide |
| title_short | Complementary pharmacological and toxicological characterization data
on the pharmacological profile of
N-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)
acetamide |
| title_sort | complementary pharmacological and toxicological characterization data
on the pharmacological profile of
n-(2,6-dichlorophenyl)-2-(4-methyl-1-piperidinyl)
acetamide |
| topic | Data Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156471/ https://www.ncbi.nlm.nih.gov/pubmed/27995169 http://dx.doi.org/10.1016/j.dib.2016.07.019 |
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