The role of HYAL2 in LSS-induced glycocalyx impairment and the PKA-mediated decrease in eNOS–Ser-633 phosphorylation and nitric oxide production

Hyaluronan (HA) in the endothelial glycocalyx serves as a mechanotransducer for high-shear-stress–stimulated endothelial nitric oxide synthase (eNOS) phosphorylation and nitric oxide (NO) production. Low shear stress (LSS) has been shown to contribute to endothelial inflammation and atherosclerosis...

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Detalles Bibliográficos
Autores principales: Kong, Xiangquan, Chen, Liang, Ye, Peng, Wang, Zhimei, Zhang, Junjie, Ye, Fei, Chen, Shaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156538/
https://www.ncbi.nlm.nih.gov/pubmed/27798230
http://dx.doi.org/10.1091/mbc.E16-04-0241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156538/
https://www.ncbi.nlm.nih.gov/pubmed/27798230
http://dx.doi.org/10.1091/mbc.E16-04-0241

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