Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models

An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on...

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Detalles Bibliográficos
Autores principales: D'Andrea, Marco, Benassi, Marcello, Strigari, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156873/
https://www.ncbi.nlm.nih.gov/pubmed/28044088
http://dx.doi.org/10.1155/2016/2796186
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author D'Andrea, Marco
Benassi, Marcello
Strigari, Lidia
author_facet D'Andrea, Marco
Benassi, Marcello
Strigari, Lidia
author_sort D'Andrea, Marco
collection PubMed
description An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points.
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spelling pubmed-51568732017-01-02 Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models D'Andrea, Marco Benassi, Marcello Strigari, Lidia Comput Math Methods Med Review Article An overview of radiotherapy (RT) induced normal tissue complication probability (NTCP) models is presented. NTCP models based on empirical and mechanistic approaches that describe a specific radiation induced late effect proposed over time for conventional RT are reviewed with particular emphasis on their basic assumptions and related mathematical translation and their weak and strong points. Hindawi Publishing Corporation 2016 2016-12-01 /pmc/articles/PMC5156873/ /pubmed/28044088 http://dx.doi.org/10.1155/2016/2796186 Text en Copyright © 2016 Marco D'Andrea et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
D'Andrea, Marco
Benassi, Marcello
Strigari, Lidia
Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_full Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_fullStr Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_full_unstemmed Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_short Modeling Radiotherapy Induced Normal Tissue Complications: An Overview beyond Phenomenological Models
title_sort modeling radiotherapy induced normal tissue complications: an overview beyond phenomenological models
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5156873/
https://www.ncbi.nlm.nih.gov/pubmed/28044088
http://dx.doi.org/10.1155/2016/2796186
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