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Aptamer-PEG-modified Fe(3)O(4)@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells

Hypoxia-induced cancer stem cells have been known to be involved in tumour metastasis, resistance to chemo/radio therapy and tumour recurrence. Magnetic Resonance Imaging is a widely used imaging tool for cancers in clinics and research. To develop T1-positive and T2-negative dual mode MRI agents fo...

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Detalles Bibliográficos
Autores principales:	Zhu, Haitao, Zhang, Lirong, Liu, Yanfang, Zhou, Yuepeng, Wang, Kang, Xie, Xiaodong, Song, Lian, Wang, Dongqing, Han, Chunlei, Chen, Qiuyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157021/ https://www.ncbi.nlm.nih.gov/pubmed/27976736 http://dx.doi.org/10.1038/srep39245

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