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Cumulative subgroup analysis to reduce waste in clinical research for individualised medicine
BACKGROUND: Although subgroup analyses in clinical trials may provide evidence for individualised medicine, their conduct and interpretation remain controversial. METHODS: Subgroup effect can be defined as the difference in treatment effect across patient subgroups. Cumulative subgroup analysis refe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157082/ https://www.ncbi.nlm.nih.gov/pubmed/27974045 http://dx.doi.org/10.1186/s12916-016-0744-x |