Suppression of ROS Production by Exendin-4 in PSC Attenuates the High Glucose-Induced Islet Fibrosis

Pancreatic stellate cells (PSCs) play a major role to fibrotic islet destruction observed in diabetic patients and animal model of diabetes. Exendin-4 (Ex-4) is a potent insulinotropic agent and has been approved for the treatment of type 2 diabetes. However, there have been no reports demonstrating...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ji-Won, Park, Shin-Young, You, Young-Hye, Ham, Dong-Sik, Lee, Seung-Hwan, Yang, Hae Kyung, Jeong, In-Kyung, Ko, Seung-Hyun, Yoon, Kun-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157943/
https://www.ncbi.nlm.nih.gov/pubmed/27977690
http://dx.doi.org/10.1371/journal.pone.0163187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157943/
https://www.ncbi.nlm.nih.gov/pubmed/27977690
http://dx.doi.org/10.1371/journal.pone.0163187

Ejemplares similares