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Characterization and Functional Analysis of Extracellular Vesicles and Muscle-Abundant miRNAs (miR-1, miR-133a, and miR-206) in C(2)C(12) Myocytes and mdx Mice
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder. Here, we show that the CD63 antigen, which is located on the surface of extracellular vesicles (EVs), is associated with increased levels of muscle-abundant miRNAs, namely myomiRs miR-1, miR-133a, and miR-206, in the sera of...
Autores principales: | Matsuzaka, Yasunari, Tanihata, Jun, Komaki, Hirofumi, Ishiyama, Akihiko, Oya, Yasushi, Rüegg, Urs, Takeda, Shin-ichi, Hashido, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158003/ https://www.ncbi.nlm.nih.gov/pubmed/27977725 http://dx.doi.org/10.1371/journal.pone.0167811 |
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