Cargando…

GSK-3β/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy

Testosterone induces cardiac hypertrophy through a mechanism that involves a concerted crosstalk between cytosolic and nuclear signaling pathways. Nuclear factor of activated T-cells (NFAT) is associated with the promotion of cardiac hypertrophy, glycogen synthase kinase-3β (GSK-3β) is considered to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duran, Javier, Oyarce, Cesar, Pavez, Mario, Valladares, Denisse, Basualto-Alarcon, Carla, Lagos, Daniel, Barrientos, Genaro, Troncoso, Mayarling Francisca, Ibarra, Cristian, Estrada, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158037/ https://www.ncbi.nlm.nih.gov/pubmed/27977752 http://dx.doi.org/10.1371/journal.pone.0168255

Ejemplares similares

Ca(2+)/Calmodulin-Dependent Protein Kinase II and Androgen Signaling Pathways Modulate MEF2 Activity in Testosterone-Induced Cardiac Myocyte Hypertrophy
por: Duran, Javier, et al.
Publicado: (2017)

Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy
por: Troncoso, Mayarling Francisca, et al.
Publicado: (2021)

Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men
por: Basualto-Alarcón, Carla, et al.
Publicado: (2021)

GDF11 Modulates Ca(2+)-Dependent Smad2/3 Signaling to Prevent Cardiomyocyte Hypertrophy
por: Duran, Javier, et al.
Publicado: (2018)

NLRP3 Inflammasome: Potential Role in Obesity Related Low-Grade Inflammation and Insulin Resistance in Skeletal Muscle
por: Jorquera, Gonzalo, et al.
Publicado: (2021)

Androgen-Regulated Cardiac Metabolism in Aging Men
por: Barrientos, Genaro, et al.
Publicado: (2020)

Exploring Regulatory Mechanisms of Atrial Myocyte Hypertrophy of Mitral Regurgitation through Gene Expression Profiling Analysis: Role of NFAT in Cardiac Hypertrophy
por: Chang, Tzu-Hao, et al.
Publicado: (2016)

A NFAT decoy approach to inhibit cardiac hypertrophy
por: Heineke, Joerg
Publicado: (2021)

How does NFAT3 regulate the occurrence of cardiac hypertrophy?
por: Hui, Wang, et al.
Publicado: (2023)

Cardiac Hypertrophy Involves Both Myocyte Hypertrophy and Hyperplasia in Anemic Zebrafish
por: Sun, Xiaojing, et al.
Publicado: (2009)

Sarcopenia and Androgens: A Link between Pathology and Treatment
por: Basualto-Alarcón, Carla, et al.
Publicado: (2014)

NULP1 Alleviates Cardiac Hypertrophy by Suppressing NFAT3 Transcriptional Activity
por: Zhang, Xin, et al.
Publicado: (2020)

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes
por: Karagiannis, Tom C, et al.
Publicado: (2010)

A perinuclear calcium compartment regulates cardiac myocyte hypertrophy
por: Turcotte, Moriah Gildart, et al.
Publicado: (2022)

Gestational diabetes triggers postpartum cardiac hypertrophy via activation of calcineurin/NFAT signaling
por: Verma, Nirmal, et al.
Publicado: (2021)

Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy
por: Bernt, Alexander, et al.
Publicado: (2016)

AAV-mediated expression of NFAT decoy oligonucleotides protects from cardiac hypertrophy and heart failure
por: Remes, Anca, et al.
Publicado: (2021)

Neuronal NO synthase mediates plenylephrine induced cardiomyocyte hypertrophy through facilitation of NFAT-dependent transcriptional activity
por: Loyer, Xavier, et al.
Publicado: (2019)

Telmisartan suppresses cardiac hypertrophy by inhibiting cardiomyocyte apoptosis via the NFAT/ANP/BNP signaling pathway
por: Li, Xiurong, et al.
Publicado: (2017)

Cordyceps militaris Fruit Body Extract Decreases Testosterone Catabolism and Testosterone-Stimulated Prostate Hypertrophy
por: Kusama, Kazuya, et al.
Publicado: (2020)

Syndecan-4 Is Essential for Development of Concentric Myocardial Hypertrophy via Stretch-Induced Activation of the Calcineurin-NFAT Pathway
por: Finsen, Alexandra V., et al.
Publicado: (2011)

Sanggenon C protects against pressure overload-induced cardiac hypertrophy via the calcineurin/NFAT2 pathway
por: Xiao, Lili, et al.
Publicado: (2017)

Betulinic Acid Protects DOX-Triggered Cardiomyocyte Hypertrophy Response through the GATA-4/Calcineurin/NFAT Pathway
por: Yoon, Jung Joo, et al.
Publicado: (2020)

Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy
por: Luo, Yuxuan, et al.
Publicado: (2021)

Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
por: Lunde, Ida G., et al.
Publicado: (2022)

PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium
por: Jin, Xian, et al.
Publicado: (2017)

Electrical Stimuli Are Anti-Apoptotic in Skeletal Muscle via Extracellular ATP. Alteration of This Signal in Mdx Mice Is a Likely Cause of Dystrophy
por: Valladares, Denisse, et al.
Publicado: (2013)

ATP-Sensitive Potassium Channel Currents in Eccentrically Hypertrophied Cardiac Myocytes of Volume-Overloaded Rats
por: Alvin, Zikiar V., et al.
Publicado: (2011)

Effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients
por: Zhang, Chen, et al.
Publicado: (2014)

Serum testosterone level correlates with left ventricular hypertrophy in older women
por: Szadkowska, Iwona, et al.
Publicado: (2023)

Lercanidipine attenuates angiotensin II-induced cardiomyocyte hypertrophy by blocking calcineurin-NFAT3 and CaMKII-HDAC4 signaling
por: Chen, Yuezhang, et al.
Publicado: (2017)

Increased sarcolemmal Na(+)/H(+) exchange activity in hypertrophied myocytes from dogs with chronic atrioventricular block
por: van Borren, Marcel M. G. J., et al.
Publicado: (2013)

Changes in N6-Methyladenosine Modification Modulate Diabetic Cardiomyopathy by Reducing Myocardial Fibrosis and Myocyte Hypertrophy
por: Ju, Wenhao, et al.
Publicado: (2021)

Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy
por: Subramaniam, Gunasekaran, et al.
Publicado: (2023)

NFAT1 and NFAT2 Differentially Regulate CTL Differentiation Upon Acute Viral Infection
por: Xu, Tianhao, et al.
Publicado: (2019)

Testosterone-induced hypertrophy, fibrosis and apoptosis of cardiac cells – an ultrastructural and immunohistochemical study
por: Papamitsou, Theodora, et al.
Publicado: (2011)

mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats
por: Chen, Jianshu, et al.
Publicado: (2021)

GSK3β Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury
por: Vainio, Laura, et al.
Publicado: (2021)

Defining the Scale to Build Complex Networks with a 40-Year Norwegian Intraplate Seismicity Dataset
por: Pavez-Orrego, Claudia, et al.
Publicado: (2023)

TrpC3 Regulates Hypertrophy-Associated Gene Expression without Affecting Myocyte Beating or Cell Size
por: Brenner, Jacob S., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_f6bju47ku4hinmtbjm35mke5mj