Inhibition of cAMP-Dependent PKA Activates β(2)-Adrenergic Receptor Stimulation of Cytosolic Phospholipase A(2) via Raf-1/MEK/ERK and IP(3)-Dependent Ca(2+) Signaling in Atrial Myocytes

We previously reported in atrial myocytes that inhibition of cAMP-dependent protein kinase (PKA) by laminin (LMN)-integrin signaling activates β(2)-adrenergic receptor (β(2)-AR) stimulation of cytosolic phospholipase A(2) (cPLA(2)). The present study sought to determine the signaling mechanisms by w...

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Detalles Bibliográficos
Autores principales: Pabbidi, M. R., Ji, X., Maxwell, J. T., Mignery, G. A., Samarel, A. M., Lipsius, S. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158063/
https://www.ncbi.nlm.nih.gov/pubmed/27977772
http://dx.doi.org/10.1371/journal.pone.0168505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158063/
https://www.ncbi.nlm.nih.gov/pubmed/27977772
http://dx.doi.org/10.1371/journal.pone.0168505

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