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Systems Based Study of the Therapeutic Potential of Small Charged Molecules for the Inhibition of IL-1 Mediated Cartilage Degradation

Inflammatory cytokines are key drivers of cartilage degradation in post-traumatic osteoarthritis. Cartilage degradation mediated by these inflammatory cytokines has been extensively investigated using in vitro experimental systems. Based on one such study, we have developed a computational model to...

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Detalles Bibliográficos
Autores principales:	Kar, Saptarshi, Smith, David W., Gardiner, Bruce S., Grodzinsky, Alan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158201/ https://www.ncbi.nlm.nih.gov/pubmed/27977731 http://dx.doi.org/10.1371/journal.pone.0168047

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