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Suppression of Medulloblastoma Lesions by Forced Migration of Preneoplastic Precursor Cells with Intracerebellar Administration of the Chemokine Cxcl3
Medulloblastoma (MB), tumor of the cerebellum, remains a leading cause of cancer-related mortality in childhood. We previously showed, in a mouse model of spontaneous MB (Ptch1(+/-)/Tis21(-/-)), that a defect of the migration of cerebellar granule neuron precursor cells (GCPs) correlates with an inc...
Autores principales: | Ceccarelli, Manuela, Micheli, Laura, Tirone, Felice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159413/ https://www.ncbi.nlm.nih.gov/pubmed/28018222 http://dx.doi.org/10.3389/fphar.2016.00484 |
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