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p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice
Loss of E-cadherin expression is causal to the development of invasive lobular breast carcinoma (ILC). E-cadherin loss leads to dismantling of the adherens junction and subsequent translocation of p120-catenin (p120) to the cytosol and nucleus. Although p120 is critical for the metastatic potential...
Autores principales: | Tenhagen, Milou, Klarenbeek, Sjoerd, Braumuller, Tanya M., Hofmann, Ilse, van der Groep, Petra, ter Hoeve, Natalie, van der Wall, Elsken, Jonkers, Jos, Derksen, Patrick W. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159444/ https://www.ncbi.nlm.nih.gov/pubmed/27411687 http://dx.doi.org/10.1007/s10911-016-9358-3 |
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