Neutrophils are Essential in Short Hairpin RNA of Indoleamine 2,3- Dioxygenase Mediated-antitumor Efficiency

Indoleamine 2,3-dioxygenase (IDO) is a rate limiting enzyme in tryptophan-degrading pathways and IDO activity results in immune suppression. Targeting IDO is a strategy of cancer immunotherapies. Our previous studies demonstrate that delivery of short hairpin against IDO (IDO shRNA) suppresses tumor...

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Detalles Bibliográficos
Autores principales: Liu, Kuan-Ting, Liu, Yao-Hua, Liu, Hsin-Liang, Chong, Inn-Wen, Yen, Meng-Chi, Kuo, Po-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159481/
https://www.ncbi.nlm.nih.gov/pubmed/27922590
http://dx.doi.org/10.1038/mtna.2016.105

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