Cargando…

Kinetics of transcription initiation directed by multiple cis-regulatory elements on the glnAp2 promoter

Transcription initiation is orchestrated by dynamic molecular interactions, with kinetic steps difficult to detect. Utilizing a hybrid method, we aim to unravel essential kinetic steps of transcriptional regulation on the glnAp2 promoter, whose regulatory region includes two enhancers (sites I and I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yaolai, Liu, Feng, Wang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159524/ https://www.ncbi.nlm.nih.gov/pubmed/27899598 http://dx.doi.org/10.1093/nar/gkw1150

Ejemplares similares

PreCisIon: PREdiction of CIS-regulatory elements improved by gene’s positION
por: Elati, Mohamed, et al.
Publicado: (2013)

Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
por: Castro-Mondragon, Jaime A, et al.
Publicado: (2022)

Retrotransposons spread potential cis-regulatory elements during mammary gland evolution
por: Nishihara, Hidenori
Publicado: (2019)

The twilight zone of cis element alignments
por: Sebastian, Alvaro, et al.
Publicado: (2013)

A correlation with exon expression approach to identify cis-regulatory elements for tissue-specific alternative splicing
por: Das, Debopriya, et al.
Publicado: (2007)

The cis-regulatory map of Shewanella genomes
por: Liu, Jiajian, et al.
Publicado: (2008)

Synthetic and genomic regulatory elements reveal aspects of cis-regulatory grammar in mouse embryonic stem cells
por: King, Dana M, et al.
Publicado: (2020)

Identification of cis-regulatory modules in promoters of human genes exploiting mutual positioning of transcription factors
por: Nandi, Soumyadeep, et al.
Publicado: (2013)

Computational identification of new structured cis-regulatory elements in the 3′-untranslated region of human protein coding genes
por: Chen, Xiaowei Sylvia, et al.
Publicado: (2012)

Towards a map of cis-regulatory sequences in the human genome
por: Niu, Meng, et al.
Publicado: (2018)

Position and distance specificity are important determinants of cis-regulatory motifs in addition to evolutionary conservation
por: Vardhanabhuti, Saran, et al.
Publicado: (2007)

Epigenetic regulation of human cis-natural antisense transcripts
por: Conley, Andrew B., et al.
Publicado: (2012)

Differences in transcription initiation directionality underlie distinctions between plants and animals in chromatin modification patterns at genes and cis-regulatory elements
por: Silver, Brianna D., et al.
Publicado: (2023)

A cis-regulatory module activating transcription in the suspensor contains five cis-regulatory elements
por: Henry, Kelli F., et al.
Publicado: (2015)

Imogene: identification of motifs and cis-regulatory modules underlying gene co-regulation
por: Rouault, Hervé, et al.
Publicado: (2014)

Peak-valley-peak pattern of histone modifications delineates active regulatory elements and their directionality
por: Pundhir, Sachin, et al.
Publicado: (2016)

Exonic remnants of whole-genome duplication reveal cis-regulatory function of coding exons
por: Dong, Xianjun, et al.
Publicado: (2010)

On the mechanistic nature of epistasis in a canonical cis-regulatory element
por: Lagator, Mato, et al.
Publicado: (2017)

Trans-kingdom rescue of Gln-tRNA(Gln) synthesis in yeast cytoplasm and mitochondria
por: Liao, Chih-Chi, et al.
Publicado: (2012)

Phosphate control over nitrogen metabolism in Streptomyces coelicolor: direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP
por: Rodríguez-García, Antonio, et al.
Publicado: (2009)

High-throughput discovery of post-transcriptional cis-regulatory elements
por: Wissink, Erin M., et al.
Publicado: (2016)

MOPAT: a graph-based method to predict recurrent cis-regulatory modules from known motifs
por: Hu, Jianfei, et al.
Publicado: (2008)

Redundancy and the Evolution of Cis-Regulatory Element Multiplicity
por: Paixão, Tiago, et al.
Publicado: (2010)

Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria
por: Shi, Jing, et al.
Publicado: (2023)

Upstream mononucleotide A-repeats play a cis-regulatory role in mammals through the DICER1 and Ago proteins
por: Aporntewan, Chatchawit, et al.
Publicado: (2013)

MMARGE: Motif Mutation Analysis for Regulatory Genomic Elements
por: Link, Verena M, et al.
Publicado: (2018)

A highly conserved cis-regulatory motif directs differential gonadal synexpression of Dmrt1 transcripts during gonad development
por: Herpin, Amaury, et al.
Publicado: (2009)

Profiling Transcription Initiation in Peripheral Leukocytes Reveals Severity-Associated Cis-Regulatory Elements in Critical COVID-19
por: Lam, Michael Tun Yin, et al.
Publicado: (2021)

Methylated cis-regulatory elements mediate KLF4-dependent gene transactivation and cell migration
por: Wan, Jun, et al.
Publicado: (2017)

Local sequence features that influence AP-1 cis-regulatory activity
por: Chaudhari, Hemangi G., et al.
Publicado: (2018)

Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants
por: Lee, Dongwon, et al.
Publicado: (2018)

Competition between the GlnR and PhoP regulators for the glnA and amtB promoters in Streptomyces coelicolor
por: Sola-Landa, Alberto, et al.
Publicado: (2013)

Genome-wide inference reveals that feedback regulations constrain promoter-dependent transcriptional burst kinetics
por: Luo, Songhao, et al.
Publicado: (2022)

The role of repressor kinetics in relief of transcriptional interference between convergent promoters
por: Hao, Nan, et al.
Publicado: (2016)

Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control
por: Zheng, Ke-wei, et al.
Publicado: (2013)

Parallel characterization of cis-regulatory elements for multiple genes using CRISPRpath
por: Ren, Xingjie, et al.
Publicado: (2021)

Human population-specific gene expression and transcriptional network modification with polymorphic transposable elements
por: Wang, Lu, et al.
Publicado: (2017)

CEAS: cis-regulatory element annotation system
por: Ji, Xuwo, et al.
Publicado: (2006)

Epistatic Interactions in the Arabinose Cis-Regulatory Element
por: Lagator, Mato, et al.
Publicado: (2016)

The Influence of cis-Regulatory Elements on DNA Methylation Fidelity
por: Teng, Mingxiang, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_4569jf3hvrm3vmtssp1360uoj9