Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα

Adaptation to fasting involves both Glucocorticoid Receptor (GRα) and Peroxisome Proliferator-Activated Receptor α (PPARα) activation. Given both receptors can physically interact we investigated the possibility of a genome-wide cross-talk between activated GR and PPARα, using ChIP- and RNA-seq in p...

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Detalles Bibliográficos
Autores principales: Ratman, Dariusz, Mylka, Viacheslav, Bougarne, Nadia, Pawlak, Michal, Caron, Sandrine, Hennuyer, Nathalie, Paumelle, Réjane, De Cauwer, Lode, Thommis, Jonathan, Rider, Mark H., Libert, Claude, Lievens, Sam, Tavernier, Jan, Staels, Bart, De Bosscher, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159533/
https://www.ncbi.nlm.nih.gov/pubmed/27576532
http://dx.doi.org/10.1093/nar/gkw742

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