RNA2DNAlign: nucleotide resolution allele asymmetries through quantitative assessment of RNA and DNA paired sequencing data

We introduce RNA2DNAlign, a computational framework for quantitative assessment of allele counts across paired RNA and DNA sequencing datasets. RNA2DNAlign is based on quantitation of the relative abundance of variant and reference read counts, followed by binomial tests for genotype and allelic sta...

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Detalles Bibliográficos
Autores principales: Movassagh, Mercedeh, Alomran, Nawaf, Mudvari, Prakriti, Dede, Merve, Dede, Cem, Kowsari, Kamran, Restrepo, Paula, Cauley, Edmund, Bahl, Sonali, Li, Muzi, Waterhouse, Wesley, Tsaneva-Atanasova, Krasimira, Edwards, Nathan, Horvath, Anelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159535/
https://www.ncbi.nlm.nih.gov/pubmed/27576531
http://dx.doi.org/10.1093/nar/gkw757

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