The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation

There is a growing perception that long non-coding RNAs (lncRNAs) modulate cellular function. In this study, we analyzed the role of the lncRNA HOTAIR in mesenchymal stem cells (MSCs) with particular focus on senescence-associated changes in gene expression and DNA-methylation (DNAm). HOTAIR binding...

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Detalles Bibliográficos
Autores principales: Kalwa, Marie, Hänzelmann, Sonja, Otto, Sabrina, Kuo, Chao-Chung, Franzen, Julia, Joussen, Sylvia, Fernandez-Rebollo, Eduardo, Rath, Björn, Koch, Carmen, Hofmann, Andrea, Lee, Shih-Han, Teschendorff, Andrew E., Denecke, Bernd, Lin, Qiong, Widschwendter, Martin, Weinhold, Elmar, Costa, Ivan G., Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159544/
https://www.ncbi.nlm.nih.gov/pubmed/27634931
http://dx.doi.org/10.1093/nar/gkw802

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