A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network

Aberrant stem cell-like gene regulatory networks are a feature of leukaemogenesis. The ETS-related gene (ERG), an important regulator of normal haematopoiesis, is also highly expressed in T-ALL and acute myeloid leukaemia (AML). However, the transcriptional regulation of ERG in leukaemic cells remai...

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Detalles Bibliográficos
Autores principales: Unnikrishnan, Ashwin, Guan, Yi F., Huang, Yizhou, Beck, Dominik, Thoms, Julie A. I., Peirs, Sofie, Knezevic, Kathy, Ma, Shiyong, de Walle, Inge V., de Jong, Ineke, Ali, Zara, Zhong, Ling, Raftery, Mark J., Taghon, Tom, Larsson, Jonas, MacKenzie, Karen L., Van Vlierberghe, Pieter, Wong, Jason W. H., Pimanda, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159545/
https://www.ncbi.nlm.nih.gov/pubmed/27604872
http://dx.doi.org/10.1093/nar/gkw804

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