Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation

Centromeres consist of DNA repeats in many eukaryotes. Non-allelic homologous recombination (HR) between them can result in gross chromosomal rearrangements (GCRs). In fission yeast, Rad51 suppresses isochromosome formation that occurs between inverted repeats in the centromere. However, how the HR...

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Detalles Bibliográficos
Autores principales: Onaka, Atsushi T., Toyofuku, Naoko, Inoue, Takahiro, Okita, Akiko K., Sagawa, Minami, Su, Jie, Shitanda, Takeshi, Matsuyama, Rei, Zafar, Faria, Takahashi, Tatsuro S., Masukata, Hisao, Nakagawa, Takuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159554/
https://www.ncbi.nlm.nih.gov/pubmed/27697832
http://dx.doi.org/10.1093/nar/gkw874

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