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Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer

The 12-subunit mammalian eIF3 is the largest and most complex translation initiation factor and has been implicated in numerous steps of translation initiation, termination and ribosomal recycling. Imbalanced eIF3 expression levels are observed in various types of cancer and developmental disorders,...

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Detalles Bibliográficos
Autores principales:	Wagner, Susan, Herrmannová, Anna, Šikrová, Darina, Valášek, Leoš Shivaya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159561/ https://www.ncbi.nlm.nih.gov/pubmed/27924037 http://dx.doi.org/10.1093/nar/gkw972

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