Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway

Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates con...

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Autores principales: Dybwad, Marius, Aarskaug, Tone, Fykse, Else-Marie, Henie Madslien, Elisabeth, Blatny, Janet Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159569/
https://www.ncbi.nlm.nih.gov/pubmed/27979936
http://dx.doi.org/10.1128/genomeA.01367-16
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author Dybwad, Marius
Aarskaug, Tone
Fykse, Else-Marie
Henie Madslien, Elisabeth
Blatny, Janet Martha
author_facet Dybwad, Marius
Aarskaug, Tone
Fykse, Else-Marie
Henie Madslien, Elisabeth
Blatny, Janet Martha
author_sort Dybwad, Marius
collection PubMed
description Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates consisted of a 3.36 Mb-chromosome, while the 2005 genomes featured an additional 68 kb-episome sharing high sequence similarity with the L. pneumophila Lens plasmid. All six genomes contained multiple mobile genetic elements including novel combinations of type-IVA secretion systems. A comparative genomics study will be launched to resolve the genetic relationship between the L. pneumophila isolates.
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spelling pubmed-51595692016-12-27 Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway Dybwad, Marius Aarskaug, Tone Fykse, Else-Marie Henie Madslien, Elisabeth Blatny, Janet Martha Genome Announc Prokaryotes Here, we report the complete genome sequences of Legionella pneumophila isolates from two collocated outbreaks of Legionnaires’ disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway. One clinical and two environmental isolates were sequenced from each outbreak. The genome of all six isolates consisted of a 3.36 Mb-chromosome, while the 2005 genomes featured an additional 68 kb-episome sharing high sequence similarity with the L. pneumophila Lens plasmid. All six genomes contained multiple mobile genetic elements including novel combinations of type-IVA secretion systems. A comparative genomics study will be launched to resolve the genetic relationship between the L. pneumophila isolates. American Society for Microbiology 2016-12-15 /pmc/articles/PMC5159569/ /pubmed/27979936 http://dx.doi.org/10.1128/genomeA.01367-16 Text en Copyright © 2016 Dybwad et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
Dybwad, Marius
Aarskaug, Tone
Fykse, Else-Marie
Henie Madslien, Elisabeth
Blatny, Janet Martha
Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway
title Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway
title_full Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway
title_fullStr Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway
title_full_unstemmed Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway
title_short Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway
title_sort complete genome sequences of six legionella pneumophila isolates from two collocated outbreaks of legionnaires’ disease in 2005 and 2008 in sarpsborg/fredrikstad, norway
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159569/
https://www.ncbi.nlm.nih.gov/pubmed/27979936
http://dx.doi.org/10.1128/genomeA.01367-16
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