Cargando…

High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies

The bacterium Nocardia terpenica IFM 0406 is known as the producer of the immunosuppressant brasilicardin A. Here, we report the completely sequenced genome of strain IFM 0406, which facilitates the heterologous expression of the brasilicardin biosynthetic gene cluster but also unveils the intriguin...

Descripción completa

Detalles Bibliográficos
Autores principales: Buchmann, Anina, Eitel, Michael, Koch, Pierre, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Wolański, Marcin, Krawiec, Michał, Zakrzewska-Czerwińska, Jolanta, Méndez, Carmen, Botas, Alma, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Gross, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159576/
https://www.ncbi.nlm.nih.gov/pubmed/27979943
http://dx.doi.org/10.1128/genomeA.01391-16
_version_ 1782481794250047488
author Buchmann, Anina
Eitel, Michael
Koch, Pierre
Schwarz, Paul N.
Stegmann, Evi
Wohlleben, Wolfgang
Wolański, Marcin
Krawiec, Michał
Zakrzewska-Czerwińska, Jolanta
Méndez, Carmen
Botas, Alma
Núñez, Luz Elena
Morís, Francisco
Cortés, Jesus
Gross, Harald
author_facet Buchmann, Anina
Eitel, Michael
Koch, Pierre
Schwarz, Paul N.
Stegmann, Evi
Wohlleben, Wolfgang
Wolański, Marcin
Krawiec, Michał
Zakrzewska-Czerwińska, Jolanta
Méndez, Carmen
Botas, Alma
Núñez, Luz Elena
Morís, Francisco
Cortés, Jesus
Gross, Harald
author_sort Buchmann, Anina
collection PubMed
description The bacterium Nocardia terpenica IFM 0406 is known as the producer of the immunosuppressant brasilicardin A. Here, we report the completely sequenced genome of strain IFM 0406, which facilitates the heterologous expression of the brasilicardin biosynthetic gene cluster but also unveils the intriguing biosynthetic capacity of the strain to produce secondary metabolites.
format Online
Article
Text
id pubmed-5159576
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-51595762016-12-27 High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies Buchmann, Anina Eitel, Michael Koch, Pierre Schwarz, Paul N. Stegmann, Evi Wohlleben, Wolfgang Wolański, Marcin Krawiec, Michał Zakrzewska-Czerwińska, Jolanta Méndez, Carmen Botas, Alma Núñez, Luz Elena Morís, Francisco Cortés, Jesus Gross, Harald Genome Announc Prokaryotes The bacterium Nocardia terpenica IFM 0406 is known as the producer of the immunosuppressant brasilicardin A. Here, we report the completely sequenced genome of strain IFM 0406, which facilitates the heterologous expression of the brasilicardin biosynthetic gene cluster but also unveils the intriguing biosynthetic capacity of the strain to produce secondary metabolites. American Society for Microbiology 2016-12-15 /pmc/articles/PMC5159576/ /pubmed/27979943 http://dx.doi.org/10.1128/genomeA.01391-16 Text en Copyright © 2016 Buchmann et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
Buchmann, Anina
Eitel, Michael
Koch, Pierre
Schwarz, Paul N.
Stegmann, Evi
Wohlleben, Wolfgang
Wolański, Marcin
Krawiec, Michał
Zakrzewska-Czerwińska, Jolanta
Méndez, Carmen
Botas, Alma
Núñez, Luz Elena
Morís, Francisco
Cortés, Jesus
Gross, Harald
High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
title High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
title_full High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
title_fullStr High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
title_full_unstemmed High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
title_short High-Quality Draft Genome Sequence of the Actinobacterium Nocardia terpenica IFM 0406, Producer of the Immunosuppressant Brasilicardins, Using Illumina and PacBio Technologies
title_sort high-quality draft genome sequence of the actinobacterium nocardia terpenica ifm 0406, producer of the immunosuppressant brasilicardins, using illumina and pacbio technologies
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159576/
https://www.ncbi.nlm.nih.gov/pubmed/27979943
http://dx.doi.org/10.1128/genomeA.01391-16
work_keys_str_mv AT buchmannanina highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT eitelmichael highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT kochpierre highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT schwarzpauln highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT stegmannevi highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT wohllebenwolfgang highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT wolanskimarcin highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT krawiecmichał highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT zakrzewskaczerwinskajolanta highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT mendezcarmen highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT botasalma highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT nunezluzelena highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT morisfrancisco highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT cortesjesus highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies
AT grossharald highqualitydraftgenomesequenceoftheactinobacteriumnocardiaterpenicaifm0406produceroftheimmunosuppressantbrasilicardinsusingilluminaandpacbiotechnologies