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Intradural-extramedullary isolated compressive sarcoid lesion

BACKGROUND: Sarcoid involvement of the central nervous system is a rare occurrence, with involvement in approximately 5–10% of all cases. Isolated spinal involvement is an even rarer encounter, only 0.3–1% of all cases. These lesions can form compressive nodules leading to myelopathy. In the present...

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Autores principales: Smith, Kyle A., Asante, Samuel K., Clough, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159688/
https://www.ncbi.nlm.nih.gov/pubmed/28028449
http://dx.doi.org/10.4103/2152-7806.194520
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author Smith, Kyle A.
Asante, Samuel K.
Clough, John
author_facet Smith, Kyle A.
Asante, Samuel K.
Clough, John
author_sort Smith, Kyle A.
collection PubMed
description BACKGROUND: Sarcoid involvement of the central nervous system is a rare occurrence, with involvement in approximately 5–10% of all cases. Isolated spinal involvement is an even rarer encounter, only 0.3–1% of all cases. These lesions can form compressive nodules leading to myelopathy. In the presented case of cervical sarcoid, the patient required a decompressive procedure to address cord compression. CASE DESCRIPTION: This is the case of a 39-year-old male presenting with cervical myelopathy caused by a compressive sarcoid nodule who underwent a successful posterior decompressive procedure. The pathology demonstrated a non-caseating granuloma, consistent with sarcoid. Postoperatively, the patient's myelopathic symptoms improved. CONCLUSIONS: Sarcoid is rarely associated with an isolated compressive cervical lesion. Although sarcoid management typically involves immune suppression, in cases of active cord compression surgical intervention is warranted.
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spelling pubmed-51596882016-12-27 Intradural-extramedullary isolated compressive sarcoid lesion Smith, Kyle A. Asante, Samuel K. Clough, John Surg Neurol Int Case Report BACKGROUND: Sarcoid involvement of the central nervous system is a rare occurrence, with involvement in approximately 5–10% of all cases. Isolated spinal involvement is an even rarer encounter, only 0.3–1% of all cases. These lesions can form compressive nodules leading to myelopathy. In the presented case of cervical sarcoid, the patient required a decompressive procedure to address cord compression. CASE DESCRIPTION: This is the case of a 39-year-old male presenting with cervical myelopathy caused by a compressive sarcoid nodule who underwent a successful posterior decompressive procedure. The pathology demonstrated a non-caseating granuloma, consistent with sarcoid. Postoperatively, the patient's myelopathic symptoms improved. CONCLUSIONS: Sarcoid is rarely associated with an isolated compressive cervical lesion. Although sarcoid management typically involves immune suppression, in cases of active cord compression surgical intervention is warranted. Medknow Publications & Media Pvt Ltd 2016-11-21 /pmc/articles/PMC5159688/ /pubmed/28028449 http://dx.doi.org/10.4103/2152-7806.194520 Text en Copyright: © 2016 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Smith, Kyle A.
Asante, Samuel K.
Clough, John
Intradural-extramedullary isolated compressive sarcoid lesion
title Intradural-extramedullary isolated compressive sarcoid lesion
title_full Intradural-extramedullary isolated compressive sarcoid lesion
title_fullStr Intradural-extramedullary isolated compressive sarcoid lesion
title_full_unstemmed Intradural-extramedullary isolated compressive sarcoid lesion
title_short Intradural-extramedullary isolated compressive sarcoid lesion
title_sort intradural-extramedullary isolated compressive sarcoid lesion
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159688/
https://www.ncbi.nlm.nih.gov/pubmed/28028449
http://dx.doi.org/10.4103/2152-7806.194520
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