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Gene expression in local stroma reflects breast tumor states and predicts patient outcome

The surrounding microenvironment has been implicated in the progression of breast tumors to metastasis. However, the degree to which metastatic breast tumors locally reprogram stromal cells as they disrupt tissue boundaries is not well understood. We used species-specific RNA sequencing in a mouse x...

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Detalles Bibliográficos
Autores principales: Bainer, Russell, Frankenberger, Casey, Rabe, Daniel, An, Gary, Gilad, Yoav, Rosner, Marsha Rich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159815/
https://www.ncbi.nlm.nih.gov/pubmed/27982086
http://dx.doi.org/10.1038/srep39240