Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis

Nonlinear responses to signals are widespread natural phenomena that affect various cellular processes. Nonlinearity can be a desirable characteristic for engineering living organisms because it can lead to more switch-like responses, similar to those underlying the wiring in electronics. Steeper fu...

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Detalles Bibliográficos
Autores principales: Senthivel, Vivek Raj, Sturrock, Marc, Piedrafita, Gabriel, Isalan, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159920/
https://www.ncbi.nlm.nih.gov/pubmed/27982133
http://dx.doi.org/10.1038/srep39178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159920/
https://www.ncbi.nlm.nih.gov/pubmed/27982133
http://dx.doi.org/10.1038/srep39178

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