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Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis
Nonlinear responses to signals are widespread natural phenomena that affect various cellular processes. Nonlinearity can be a desirable characteristic for engineering living organisms because it can lead to more switch-like responses, similar to those underlying the wiring in electronics. Steeper fu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159920/ https://www.ncbi.nlm.nih.gov/pubmed/27982133 http://dx.doi.org/10.1038/srep39178 |