Galectin-3 Induces a Pro-degradative/inflammatory Gene Signature in Human Chondrocytes, Teaming Up with Galectin-1 in Osteoarthritis Pathogenesis

Inflammatory chemo- and cytokines and matrix-degrading proteases underlie the progression of osteoarthritis (OA). Aiming to define upstream regulators for these disease markers, we pursued initial evidence for an upregulation of members of the adhesion/growth-regulatory galectin family. Immunohistoc...

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Detalles Bibliográficos
Autores principales: Weinmann, Daniela, Schlangen, Karin, André, Sabine, Schmidt, Sebastian, Walzer, Sonja M., Kubista, Bernd, Windhager, Reinhard, Toegel, Stefan, Gabius, Hans-Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159921/
https://www.ncbi.nlm.nih.gov/pubmed/27982117
http://dx.doi.org/10.1038/srep39112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159921/
https://www.ncbi.nlm.nih.gov/pubmed/27982117
http://dx.doi.org/10.1038/srep39112

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