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Differential activation of RAW 264.7 macrophages by size-segregated crystalline silica

BACKGROUND: Occupational exposure to crystalline silica is a well-established occupational hazard. Once in the lung, crystalline silica particles can result in the activation of alveolar macrophages (AM), potentially leading to silicosis, a fibrotic lung disease. Because the activation of alveolar m...

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Detalles Bibliográficos
Autores principales: Mischler, Steven E., Cauda, Emanuele G., Di Giuseppe, Michelangelo, McWilliams, Linda J., St. Croix, Claudette, Sun, Ming, Franks, Jonathan, Ortiz, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159951/
https://www.ncbi.nlm.nih.gov/pubmed/28018477
http://dx.doi.org/10.1186/s12995-016-0145-2