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In situ transduction of stromal cells and thymocytes upon intrathymic injection of lentiviral vectors
BACKGROUND: The thymus is the primary site for T-cell development and induction of self-tolerance. Previous approaches towards manipulation of T-cell differentiation have used intrathymic injection of antigens, as proteins, cells or adenoviruses, leading to transient expression of the foreign protei...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2004
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516029/ https://www.ncbi.nlm.nih.gov/pubmed/15318949 http://dx.doi.org/10.1186/1471-2172-5-18 |