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Complementing genomics and transcriptomics: Phosphoproteomics illuminates systems biology in prostate cancer

Integration of phosphoproteomics with traditional genomics and transcriptomics provides a more comprehensive overview of the signaling networks in advanced prostate cancer for immediate preclinical and future clinical use. Our recent publication introduces computational approaches for integrating th...

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Detalles Bibliográficos
Autores principales: Tan, Victor M., Cheng, Larry C., Drake, Justin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5160408/
https://www.ncbi.nlm.nih.gov/pubmed/28090583
http://dx.doi.org/10.1080/23723556.2016.1246075
Descripción
Sumario:Integration of phosphoproteomics with traditional genomics and transcriptomics provides a more comprehensive overview of the signaling networks in advanced prostate cancer for immediate preclinical and future clinical use. Our recent publication introduces computational approaches for integrating the phosphoproteome, specifically with the intent of identifying important kinase signaling networks in advanced-stage prostate cancer.